Luxury boutique stays in the heart of Rome.

Refined boutique stays with modern comfort, warm interiors and a touch of Italian elegance, steps from the city’s most loved landmarks.

  • Considered design Modern furniture, warm colours, thoughtful detail.
  • Prime locations Near the Vatican, the Colosseum and the Spanish Steps.
  • Stay as you wish From a single night, with flexible rates.
  • Book your way Direct with us or through Booking.com.
Budget Double Room 9.4Exceptional View boutique

Via Cola di Rienzo

Budget Double Room

Ventuno Dei Luxury Suites – Via Cola di Rienzo in Rome offers a central position with…

  • 2 guests
  • Studio
  • 1 bath
Deluxe King Room 9.4Exceptional View boutique

Via Cola di Rienzo

Deluxe King Room

Ventuno Dei Luxury Suites – Via Cola di Rienzo in Rome offers a central position with…

  • 2 guests
  • Studio
  • 1 bath
Deluxe Room 9.4Exceptional View boutique

Via Cola di Rienzo

Deluxe Room

Ventuno Dei Luxury Suites – Via Cola di Rienzo in Rome offers a central position with…

  • 2 guests
  • Studio
  • 1 bath
King Room 9.4Exceptional View boutique

Via Cola di Rienzo

King Room

Ventuno Dei Luxury Suites – Via Cola di Rienzo in Rome offers a central position with…

  • 2 guests
  • Studio
  • 1 bath
King Room with Spa Bath 9.4Exceptional View boutique

Via Cola di Rienzo

King Room with Spa Bath

Ventuno Dei Luxury Suites – Via Cola di Rienzo in Rome offers a central position with…

  • 2 guests
  • Studio
  • 1 bath
Superior King Room 9.4Exceptional View boutique

Via Cola di Rienzo

Superior King Room

Ventuno Dei Luxury Suites – Via Cola di Rienzo in Rome offers a central position with…

  • 2 guests
  • Studio
  • 1 bath
Deluxe Double Room 8.3Excellent View boutique

San Giovanni

Deluxe Double Room

Ventuno Dei Luxury Suites – San Giovanni in Rome offers family rooms with private bathrooms, air-conditioning,…

  • 2 guests
  • Studio
  • 1 bath
Deluxe Double Room 8.3Excellent View boutique

San Giovanni

Deluxe Double Room

Ventuno Dei Luxury Suites – San Giovanni in Rome offers family rooms with private bathrooms, air-conditioning,…

  • 2 guests
  • Studio
  • 1 bath
Economy Double Room 8.3Excellent View boutique

San Giovanni

Economy Double Room

Ventuno Dei Luxury Suites – San Giovanni in Rome offers family rooms with private bathrooms, air-conditioning,…

  • 2 guests
  • Studio
  • 1 bath
Queen Room with Jacuzzi 8.3Excellent View boutique

San Giovanni

Queen Room with Jacuzzi

Ventuno Dei Luxury Suites – San Giovanni in Rome offers family rooms with private bathrooms, air-conditioning,…

  • 2 guests
  • Studio
  • 1 bath

Ventuno Dei offers boutique hotel stays in luxury suites in the heart of Rome, designed around one simple promise: an excellent guest experience, built on quality and prime location.

A more personal way to stay in Rome.

Every boutique hotel balances comfort, modern charm and a touch of Italian character. Ventuno Dei means “Twenty-One Gods”, and each suites carries the name of one, a quiet nod to Rome’s heritage in an otherwise modern, welcoming home.

Discover the luxury suites

In the heart of Rome

Landmarks, restaurants and hidden gems just around the corner, yet each district feels surprisingly calm.

Via Cola di Rienzo

Via Cola di Rienzo, located in Rome’s elegant Prati district near Vatican City, is a vibrant avenue that blends neighborhood charm with an international feel

San Giovanni

San Giovanni, also referred to as Appio-Latino, is a vibrant historic district in southeastern Rome that seamlessly combines ancient heritage with contemporary city life.

What guests say

10
Communication with owner & Niki . Quick and easy check in & out. Niki who took care about our check in was amazing with her attitude and all information what she gave, then you don’t need to question anything more. And what was amazing, after whole day of visiting of nice places in Rome you can enjoy nice jacuzzi in your room. Nothing to complain
Monika Netherlands Stayed in King Room with Spa Bath
10
The property was beautifully decorated, modern and very clean. The room was comfortable and had a lovely luxurious feel to it. The location was excellent for exploring Rome, with many restaurants, shops and attractions within easy reach. The breakfast included with our stay wasn’t in the same building, but it was absolutely amazing and definitely worth the short walk. Overall, it was a lovely place to stay and made a great base for our trip.
Kerry United Kingdom Stayed in Budget Double Room
10
It was incredible. The host was so so nice and polite. It was very nice, clean and cozy. All perfect
Aleksandar Servia Stayed in Superior King Room
10
The room was clean and updated. The neighborhood had writing on walls, but overall felt very safe. Also, did not realize that there was a common area and 4 private rooms. But we never heard or neighbors.
Barta United States Stayed in Deluxe Double Room
10
The apartment is located in a very quiet neighborhood, just a short walk from Re Di Roma metro station. The room was clean, peaceful, and comfortable. Special thanks to Irina for the smooth check-in and for being so responsive and helpful with all our questions and requests. Everything was handled quickly and efficiently. We had a lovely stay!
Qnyaz Azerbaijan Stayed in Economy Double Room
10
Super clean rooms and great localization, it was close to tasty restaurants ;) good contact with a facility manager :) 10/10
Patrycja Poland Stayed in Queen Room with Jacuzzi
10
Good property room was safe and secure. Staff was helpful with local events. Immediately after booking Matteo and Irina reached out to me to help me with my accommodations and to assist me in getting to the property. Irina was a great help in learning about local tourists spots.
Alejandro United States Stayed in Deluxe Double Room

Questions before you book

Can’t find what you are looking for? Write to us and we will gladly help.

Contact us

You can view live availability and book instantly through our listings on Booking.com, or book directly on our website.

We recommend booking as early as possible, especially for spring, autumn and holiday periods when Rome is at its busiest. Last-minute stays are often possible, subject to availability.

We welcome short stays: the minimum is just 1 night. Any exceptions for particular dates are always shown at the time of booking.

It depends on the rate you book. We offer flexible rates with free cancellation up to a set number of days before arrival, as well as discounted non-refundable rates. The exact terms are shown before you confirm and are stated in your booking confirmation.

Yes. Changes such as dates or guest numbers can usually be arranged, subject to availability and your rate’s conditions. You can manage your reservation through Booking.com, or contact us and we will be glad to help.

Your stay in Rome starts here.

Whether you are here to explore or simply to relax, we have got you covered. Book your stay today and let us take care of the rest.

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